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Injections

Injections

Injectable therapy is a common treatment option utilized by many dermatologists for certain conditions. Several categories of injectable therapies are available that your Advanced Dermatology provider can take advantage of to treat your skin. Below is a list of the common classes of injectables and there uses.

Antibiotics: these are substances that either eliminate or inhibit the growth of microorganisms. Several classifications of microorganisms exist, with specific antibiotics targeting each class.

Antibacterials: these work by inhibiting several components of bacterial organisms, either directly killing them (bactericidal) or inhibiting their proliferation (bacteriostatic). While penicillins and cephalosporins are available for intramuscular injection, they are rarely used except for the treatment of sexually transmitted infections.

Antivirals: these work via three mechanisms – destroying virus (viricidal), stimulating the immune system (immune-enhancers) and destructive to cells (cytodestructive). Currently only cytodestructive therapies are injectable, including candida antigen and bleomycin. These are good options for warts.

Immunosuppressives: medications that inhibit or modulate the immune system have been used in dermatology for several decades, while newer more specific medications are continuously being developed. The following is a list of injectable medications available that alter the immune system for therapeutic benefit.

TNF-alpha inhibitors: the two medications dermatologists commonly use are Enbrel (etanercept) and Humira (Adalimumab). These revolutionary medications have changed the treatment paradigm in psoriasis (and its associated arthritis) and are starting to show promise in many other dermatologic conditions including neutrophil-causing disorders, autoimmune diseases, granulomatous dermatoses, blistering conditions and blood vessel inflammation problems (vasculitis). While considered by some to be somewhat new kids on the block, when effective these medications provide remarkable relief.

Stelara: the newest therapy on the market for psoriasis and psoriatic arthritis, stelara (ustekinumab) targets a specific molecule common to the expansion of the immune system involved in forming the plaques. This ground-breaking therapy is easily administered in the clinic and has the longest lasting effect than all other therapies, up to 3 months between treatments. With all therapies, there are specific side effects so make your appointment to discuss this option today.

Methotrexate: discovered over 60 years ago, methotrexate has both immunosuppressive and chemotherapeutic properties making it suitable for treatment of numerous inflammatory skin conditions at appropriate doses. Used by rheumatologists for several arthritis-associated conditions and oncologists for several malignancies, dermatologists have experience with this in cutaneous malignancies (Sezary syndrome) and numerous inflammatory skin diseases (Psoriasis, Atopic Dermatitis, Blistering skin diseases, autoimmune skin diseases, blood vessel inflammatory diseases and many others). Make an appointment today to discuss this beneficial treatment option.

Interferons: rarely used anymore in dermatology, these are FDA-approved for the treatment of genital warts. They have been used as alternative therapy for other skin problems including keloids, vascular lesions (angiomas), and systemically for neoplastic and autoimmune conditions.

Anti-platelet agents: heparin is a self-administered blood thinner in patients to prevent blood clots. In dermatology a few uses of this have been reported include necrobiosis lipoidica and chronic urticarial, but these are not usual first line options.

Steroids: intralesional (IL) and intramuscular (IM) corticosteroids are an excellent therapeutic option for numerous inflammatory skin conditions like acne lesions, cysts, eczema, contact dermatitis, amongst others. There are a few available injectable steroids which have different potencies, requiring a comprehensive knowledge to effectively administer these medications. Your Advanced Dermatology provider has extensive experience using this treatment modality to appropriately treat the specific location(s) and severity of your skins ailment. Don’t let your skin continue to suffer, call for an appointment today.

Chemotherapeutics: Bleomycin, mentioned above for warts, can also be used as an injectable therapy for various cutaneous malignancies and tumors. Though not as popular anymore, this remain an option for therapy if other treatments are not successful. Ask your provider today about the benefits of this option for your skin.